Endocrine Abstracts

Case: A 38-year-old HIV positive lady presented with a neck swelling and neutropenic sepsis. Examination of the neck revealed a firm diffuse non-tender goitre with cervical lymphadenopathy. She also had generalised lymphadenopathy, splenomegaly and miliary opacities in the lungs on the chest radiograph. Disseminated cryptococcal infection was diagnosed following isolation of the organism in blood and bone marrow. A radioisotope scan of the thyroid showed no uptake in the right...

Introduction: 18-hydroxycortisol (18-OHF) is known to be elevated in glucocorticoid remediable aldosteronism but there are few data relating to 18-OHF in the differential diagnosis of primary aldosteronism.Aim: We evaluated the usefulness of lying and standing 18-OHF in patients with primary aldosteronism in differentiating between aldosteronoma, bilateral adrenal hyperplasia (BAH) and normality.Methods: Patients (n=27) with...